PurAffin® Ligands are chemically stabilized peptide ligands (peptidomimetics) that combine the specificity and affinity of antibodies with the tractability of small molecules. PurAffin ligands can easily be manufactured in large quantities by chemical synthesis.

PurAffin columns can be stored at room temperature for months and tolerate harsh clean-in-place procedures as well as organic solvents.

3B Pharmaceuticals is selecting PurAffin ligand candidates from vast peptide libraries with a complexity of up to 1014 different peptides. The resulting ligands are subsequently optimized by peptide/peptidomimetic chemistry and conjugated to a suitable resin matrix.

Getting access to PurAffin

3B Pharmaceuticals is developing custom PurAffin® ligands and resins for any given biological. PurAffin® is licensed to the customer exclusively or non-exclusively for applications in DSP. 3B Pharmaceuticals can supply ready-to-use lab scale columns. Following the custom PurAffin® ligand and resin development, the customer has the option to access full support for upscaling and large scale process implementation of their custom PurAffin® purification product.

Supported by the Federal Ministry
or Economic Affairs and Energy according to a decision of
the German Federal Parliament.

PurAffin is a registered trademark of 3B Pharmaceuticals GmbH.