PurAffin® Ligands are chemically stabilized peptide ligands (peptidomimetics) that combine the specificity and affinity of antibodies with the tractability of small molecules. PurAffin ligands can easily be manufactured in large quantities by chemical synthesis.
PurAffin columns can be stored at room temperature for months and tolerate harsh clean-in-place procedures as well as organic solvents.
3B Pharmaceuticals is selecting PurAffin ligand candidates from vast peptide libraries with a complexity of up to 1014 different peptides. The resulting ligands are subsequently optimized by peptide/peptidomimetic chemistry and conjugated to a suitable resin matrix.