Technology

PurAffin® Ligands are chemically stabilized peptide ligands (peptidomimetics) that combine the specificity and affinity of antibodies with the tractability of small molecules. PurAffin ligands can easily be manufactured in large quantities by chemical synthesis.

PurAffin columns can be stored at room temperature for months and tolerate harsh clean-in-place procedures as well as organic solvents.

3B Pharmaceuticals is selecting PurAffin ligand candidates from vast peptide libraries with a complexity of up to 10¹⁴ different peptides. The resulting ligands are subsequently optimized by peptide/peptidomimetic chemistry and conjugated to a suitable resin matrix.

Getting access to PurAffin

3B Pharmaceuticals is developing custom PurAffin® ligands and resins for any given biological. PurAffin® is licensed to the customer exclusively or non-exclusively for applications in DSP. 3B Pharmaceuticals can supply ready-to-use lab scale columns. Following the custom PurAffin® ligand and resin development, the customer has the option to access full support for upscaling and large scale process implementation of their custom PurAffin® purification product.